Quantifying heterogeneous structure-function relationships one molecule at a time presents challenges for theory, experiment, and data analysis. We must develop new methods to collect, process, and understand super-resolved spectroscopic data to respond to the challenges of today's scientific problems. As such, our research focuses on three linked objectives:

Develop new spectroscopic data acquisition and analysis methods to image dynamics at nanoscale interfaces
Define testable hypotheses for protein separations by combining super-resolved protein adsorption and a stochastic theory of ion-exchange chromatography
Design methods to control photocatalysis at nanoparticle interfaces with the ultimate goal of controlling single electron transfer

Predictive Separations

Spectro-electrochemistry

Protein Dynamics at Interfaces

Computational Imaging/AI/Data Science

Interfacial energy and charge transfer in hybrid nanomaterials

Carlin, C.C., Dai, A.X., Al-Zubeidi, A., Simmerman, E.M., Oh, H., Gross, N., Lee S.A., Link, S., Landes, C.F., da Jornada, F.H., Dionne, J.A., "Nanoscale and ultrafast in situ techniques to probe plasmon photocatalysis" Chem. Phys. Rev. 2023, 4, 4, 041309

Nanoscale and ultrafast in situ techniques to probe plasmon photocatalysis

Gross, N., Wang, W., Brasel, S.,Searles, E.K, Bourgeois,B.,Dionne, J.A.,Landes, C. F., Link,S., "High-Throughput Screening of Optical Properties of Glass-Supported Plasmonic Nanoparticles Fabricated by Polymer Pen Lithography" J. Phys. Chem. C 2023, 127, 39, 19607–19619

High-Throughput Screening of Optical Properties of Glass-Supported Plasmonic Nanoparticles Fabricated by Polymer Pen Lithography

Jones, A.,Searles, E.K, Mayer,M.,Hoffmann, M., Gross, N., Oh, H., Fery, A., Link,S.,Landes, C. F., "Active Control of Energy Transfer in Plasmonic Nanorod–Polyaniline Hybrids " J. Phys. Chem. Lett. 2023, 14, 36, 8235–8243

Active Control of Energy Transfer in Plasmonic Nanorod–Polyaniline Hybrids

Oh, H.,Searles, E.K, Chatterjee,S.,Jia, Z., Lee, S.A., Link,S.,Landes, C. F., "Plasmon Energy Transfer Driven by Electrochemical Tuning of Methylene Blue on Single Gold Nanorods " ACS Nano 2023, 17, 18, 18280–18289

Plasmon Energy Transfer Driven by Electrochemical Tuning of Methylene Blue on Single Gold Nanorods

Gross, N.,Kuhs, C.T, Ostovar,B.,Chiang, W.Y., Wilson, K.S., Volek,T.S., Faitz,Z.M., Carlin, C.C., Dionne, J.A., Zanni, M.T., Gruebele,M., Roberts,S.T., Link,S.,Landes, C. F., "Progress and Prospects in Optical Ultrafast Microscopy in the Visible Spectral Region: Transient Absorption and Two Dimensional Microscopy " J. Phys. Chem. C 2023, 127, 30, 14557–14586

Progress and Prospects in Optical Ultrafast Microscopy in the Visible Spectral Region: Transient Absorption and Two Dimensional Microscopy

Duan, H., Jia,Z., Liaqat, M. ,Mellor, M.D., Tan,H., Nieh, M.P., Lin, Y., Link, S., Landes, C. F., He,J., "Site-Specific Chemistry on Gold Nanorods: Curvature-Guided Surface Dewetting and Supracolloidal Polymerization ACS Nano 2023 (2023)

Site-Specific Chemistry on Gold Nanorods: Curvature-Guided Surface Dewetting and Supracolloidal Polymerization

Fan, D.,Bajgiran,R.S.,Samghabadi,S.F. ,Dutta, C., Gillett,E., Rossky, P.J., Conrad, J.C., Marciel, B.A., Landes, C. F., "Imaging Heterogeneous 3D Dynamics of Individual Solutes in a Polyelectrolyte Brush Langmuir 2023, 39, 24, 8532–8539 (2023)

Imaging Heterogeneous 3D Dynamics of Individual Solutes in a Polyelectrolyte Brush

Al-Zubeidi, A.,Wang,Y.,Lin,J.,Flatebo, C., Landes C. F., Ren, H., Link, S., "d-Band Holes React at the Tips of Gold Nanorods J. Phys. Chem. Lett. 2023, 14, 23, 5297–5304 (2023)

Wallum,A.,Liu,Z.,Lee,J.,Chatterjee, S., Tauzin,L., Barr, C.D., Brown,A., Landes, C. F., Nicely, A.L., Gruebele, M., "An Instrument Assembly and Data Science Lab for Early Undergraduate Education J. Chem. Educ. 2023 (2023)

An Instrument Assembly and Data Science Lab for Early Undergraduate Education

Lee, S.A.,Kuhs, C.T., Searles,E.K.,Everitt, H.O., Link,S., Landes, C. F., "d-Band Hole Dynamics in Gold Nanoparticles Measured with Time-Resolved Emission Upconversion Microscopy Nano Lett. 2023, 23, 8, 3501–3506 (2023)

d-Band Hole Dynamics in Gold Nanoparticles Measured with Time-Resolved Emission Upconversion Microscopy

Gross, N.,Madadi, M., Ostovar,B., Dongare, P. D., McCarthy,L.A., Chiang, W.Y., Chang, W.S.,Halas,N.J., Landes, C. F.,Sader, J.E., Link,S., "Strong Substrate Binding Modulates the Acoustic Quality Factors in Gold Nanodisks J. Phys. Chem. C 2023, 127, 10, 5054–5066 (2023)

Strong Substrate Binding Modulates the Acoustic Quality Factors in Gold Nanodisks

Al-Zubeidi, A.,Ostovar, B., Carlin, C.C., Cam Li,B., Lee, S.A., Chiayng,W.Y., Gross, N., Dutta, S., Misiura, A., Searles, E.K., Chakraborty, A., Roberts, S.T., Dionne, J.A., Rossky, P.J., Landes C. F., Link,S., "Mechanism for plasmon-generated solvated electrons Proceedings of the National Academy of Sciences of the United States of America. , 2023, Vol.120(3), p.e2217035120 (2023)